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The Differences Between Juvederm and Restylane Kysse for Lips

May 2, 2025

If you’re considering lip enhancement, you’ve likely encountered two leading options: Juvederm and Restylane Kysse. Both are hyaluronic acid fillers designed to add volume, enhance shape, and improve lip texture—but they differ in important ways that might make one a better choice for your specific goals.

At Body+Beauty Lab, we offer both options and customize our recommendations based on each client’s unique anatomy and aesthetic desires. This comprehensive comparison will help you understand the key differences between these popular lip fillers.

Composition and Technology

Juvederm

  • Technology: HYLACROSS™ or VYCROSS™ technology (depending on the specific Juvederm product)
  • Consistency: Smooth, gel-like texture with high viscosity
  • Crosslinking: Higher degree of crosslinking, creating a more structured gel
  • HA Concentration: Typically contains 24mg/ml of hyaluronic acid
  • For lips: Juvederm Ultra XC and Juvederm Volbella XC are most commonly used

Restylane Kysse

  • Technology: XpresHAn Technology™ (pronounced “expression”)
  • Consistency: Softer, more flexible gel
  • Crosslinking: Optimal Balanced Technology (OBT) for tailored crosslinking
  • HA Concentration: Contains 20mg/ml of hyaluronic acid
  • Design: Specifically formulated for lips (versus general Juvederm products adapted for lips)

Results and Aesthetic Differences

Volume and Projection

Juvederm:

  • Creates more pronounced volume and projection
  • Excellent for significant volumization
  • Can create more dramatic results when desired
  • Ultra XC provides more fullness, while Volbella offers subtler enhancement

Restylane Kysse:

  • Provides moderate, natural-looking volume
  • Focuses on natural enhancement rather than dramatic volumization
  • Integrates well with surrounding tissues for subtle plumping
  • XpresHAn Technology allows for flexibility with expressions

Texture and Feel

Juvederm:

  • Tends to attract more water, potentially creating a softer feel
  • Some patients report feeling the product in their lips
  • Firm enough to provide structure and support

Restylane Kysse:

  • Designed to feel exceptionally natural in the lips
  • Moves naturally with your expressions
  • Patients often report forgetting they have filler
  • Clinical studies show 98% of patients reported natural-feeling lips

Definition and Border Enhancement

Juvederm:

  • Excellent for overall volumization
  • Can sometimes create a softer, less defined border
  • Volbella works well for subtle definition and vertical lip lines

Restylane Kysse:

  • Superior for enhancing lip borders and definition
  • Creates crisp, clean lines at the vermilion border
  • Excellent for cupid’s bow definition
  • Particularly good for enhancing natural lip shape

Ready To Learn More About Lip Fillers?

At Body+Beauty Lab, our experts can help determine which treatment—or combination of treatments—will best address your unique concerns. We offer comprehensive consultations to create a personalized treatment plan tailored to your skin’s needs and your aesthetic goals.

Ready to learn more about Lip Fillers? Contact us today to schedule your consultation and discover which lip filler product option is right for you.

 

 

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